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Merial Frontline Plus Flea and Tick Control for Dogs and Puppies

Merial Frontline Plus Flea and Tick Control for Dogs and Puppies

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Merial Frontline Plus Flea and Tick Control for Dogs and Puppies

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  • Longest-lasting, most complete spot-on flea and tick protection available

  • Flea treatment kills 100% of adult fleas on your dog within 24-48 hours

  • Kills all stages of 4 major ticks including the ones that may transmit Lyme disease and Rocky Mountain spotted fever

  • Frontline ® flea and tick keeps killing fleas and ticks for at least four weeks


FRONTLINE Plus for Dogs Flea and Tick Treatment

FRONTLINE ® Plus for Dogs provides fast, effective and convenient treatment and control of fleas and ticks for dogs and puppies. FRONTLINE® Plus stops and prevents infestations and kills adult fleas, flea eggs, and flea larvae. This effective flea treatment prevents all flea stages (eggs, larvae, pupae) from developing and kills fleas that may cause flea allergy dermatitis. Frontline flea and tick treatment also kills all stages of deer ticks (which may carry Lyme disease), brown dog ticks, American dog ticks, and lone star ticks, while preventing and controlling re-infestations. Ticks are more than a nuisance- in some cases, they may transmit serious diseases to your dog or even to you. To kill ticks that may carry and transmit these serious diseases, count on the control of FRONTLINE ® Plus.

FRONTLINE ® Plus For Dogs contains fipronil and the insect growth regulator (IGR) (S)-methoprene. Insect growth regulators interrupt or inhibit the life cycle of a pest. Flea eggs and flea larvae that are exposed to (IGR) (S)-methoprene will never develop into the adult jumping, biting and (most important) reproducing fleas. FRONTLINE ® flea and tick treatment effectively targets all stages of fleas and ticks. Fipronil collects in the oils of the skin and hair follicles, and continues to be released from hair follicles onto the skin and coat, resulting in effective tick and flea control for long-lasting activity against fleas and ticks.

FRONTLINE ® Plus for Dogs is waterproof, since the active ingredient in FRONTLINE ® products is stored in the oil glands within the skin, from which it is continuously released onto dogs' fur, FRONTLINE ® flea and tick treatment remains truly waterproof for 30 days or longer. FRONTLINE ® is so gentle it is approved for use on puppies 8 weeks or older. It is also approved for breeding, pregnant and lactating dogs. For best flea control and effective tick control, apply FRONTLINE ® Plus monthly throughout the year. FRONTLINE ® does not expire if it remains unopened and is stored properly according to the package instructions.




It is a violation of Federal Law to use this product in a manner inconsistent with its labeling. Do not allow children to apply product. To prevent harm to you and your pet, read entire label and directions before each use. Follow all directions and precautionary statements carefully. Use on dogs only. Do not use on rabbits. Do not use on other animals.

To kill fleas and all stages of brown dog ticks, American dog ticks, lone star ticks, and deer ticks (which may carry Lyme disease), apply to dogs or puppies (8 weeks or older) as follows:

  1. Remove applicator from child-resistant package.
  2. Hold applicator upright and snap applicator tip away from face and body.
  3. Place applicator tip through animal's hair to the skin level between the shoulder blades.
  4. Squeeze applicator, applying entire contents in a single spot to the animal's skin. Avoid superficial application to the animal's hair. Only one applicator per treatment is needed.


When used monthly, FRONTLINE ® Plus for Dogs completely breaks the flea life cycle and controls tick infestations. Research demonstrates that FRONTLINE ® Plus kills adult fleas, flea eggs, and flea larvae for up to three months. FRONTLINE ® Plus also prevents development of all flea stages for up to three months. FRONTLINE ® Plus kills ticks for at least one month. A once monthly application is recommended where tick control is needed. Although FRONTLINE ® Plus can control fleas for up to three months, if there is a high risk of reinfestation or if the pet has fleas which may cause flea allergy dermatitis, a once monthly application may be needed.

FRONTLINE ® Plus for Dogs remains effective even after bathing, water immersion, or exposure to sunlight. Avoid contact with treated area until dry. Do not reapply FRONTLINE ® Plus for 30 days.

Precautionary Statements

Hazards to Humans
Harmful if swallowed. Causes eye irritation. Avoid contact with skin, eyes or clothing. Wash thoroughly with soap and water after handling.

Hazards to Domestic Animals
For external use only. Do not use on puppies under 8 weeks of age. Individual sensitivities, while rare, may occur after using any pesticide product. Pets may experience some temporary irritation at the site of product application. If signs persist, or become more severe within a few days of application, consult a veterinarian immediately. Certain medications can interact with pesticides. Consult a veterinarian before using on medicated, debilitated, aged, pregnant, or nursing animals.

Physical or Chemical Hazards

  • Combustible: Do not use or store near heat or open flame.



Do not contaminate water, food, or feed by storage and disposal.

Store unused product in original container only, out of reach of children and animals.

Pesticide Disposal:
Waste resulting from use of this product may be disposed of on-site or at an approved waste disposal facility.

Container Disposal:
Securely wrap original container in several layers of newspaper and discard in trash.

First Aid:
Have the product container or label with you when calling a poison control center or doctor, or going for treatment.

  • If Swallowed: Call a poison control center or doctor immediately for treatment advice. Have person sip a glass of water if able to swallow. Do not induce vomiting unless told to do so by a poison control center or doctor. Do not give anything by mouth to an unconscious person.
  • If in Eyes: Flush eyes with plenty of water. Call a doctor if irritation persists.
  • If on Skin: Wash with plenty of soap and water. Get medical attention if irritation persists.


Call 1-800-660-1842 for 24-hour assistance



Active Ingredients: fipronil: 9.8%, (S)-methoprene: 8.8%
Inert Ingredients: 81.4%

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